← Galen

Against Those Who Have Written on Disease Patterns

§3#1

Diagnosis by Correspondence and Overlapping Paroxysms

The author criticizes those who limit periods to three but diagnose them based on the correspondence of paroxysms, demonstrating through hypothetical schedules that they fail to account for the temporal coincidence of different paroxysms.

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§3

​#1 Λέγωμεν δ’ ἐφεξῆς περὶ τῶν μόνας τὰς τρεῖς ἡγουμένων, οὐ μὴν ἐκ τῆς ἰδίας φύσεως ἑκάστην διαγινωσκόντων, ἀλλ’ ἐκ τῶν κατὰ τοὺς παροξυσμοὺς ἀνταποδόσεων.1 οὕτω γὰρ εἰώθασιν ὀνομάζειν αὐτοὶ τὰς ἀναλογίας τῶν παροξυσμῶν. οἱ τοιοῦτοι δ’ εἰ μὴ διὰ παντὸς, ὥσπερ οἱ πρότεροι, τὸν ἐσόμενον παροξυσμὸν ἀγνοήσουσιν, ἀλλὰ μέχρι τῆς τετάρτης ἢ πέμπτης ἡμέρας ἐξ ἀνάγκης. ὑποκείσθω γὰρ ἐν μὲν τῇ πρώτῃ τῶν ἡμερῶν ἕνα γεγονέναι παροξυσμὸν, ἐν δὲ τῇ δευτέρᾳ δύο, καὶ δύο πάλιν ἐν τῇ τρίτῃ, καὶ δύο κατὰ τὴν τετάρτην. ἐνδέχεται μὲν οὖν καὶ τοιαύτην εἶναι τὴν ἐπιπλοκὴν τῶν ἁπλῶν περιόδων, ὡς ἐν τῇ πρώτῃ τῶν ἡμερῶν ἀμφημερινὸν ἦρχθαι·2 κατὰ δὲ τὴν δευτέραν τριταῖον· ἐν δὲ τῇ τρίτῃ δύνασθαι μὲν καὶ τριταῖον, δύνασθαι δὲ καὶ τεταρταῖον, ἄδηλον γὰρ τοῦτο πρὸ τῆς πέμπτης, εἶτ’ ἐν τῇ τετάρτῃ τοῦ τε κατὰ τὴν πρώτην ἡμέραν ἀρξαμένου τεταρταίου δεύτερον παροξυσμὸν, καὶ τοῦ κατὰ τὴν δευτέραν τριταίου δεύτερον. εὔδηλον δὲ ὡς ἡ πέμπτη τῶν ἡμερῶν δύο παροξυσμοὺς ἕξει, τοῦ τε κατὰ τὴν τρίτην ἡμέραν ἀρξαμένου τριταίου τὸν δεύτερον καὶ τοῦ κατὰ τὴν δευτέραν ἡμέραν ἀρξαμένου τεταρταίου τὸν δεύτερον· ἡ δ’ ἕκτη τοῦ κατὰ τὴν τρίτην ἠργμένου τεταρταίου τὸν δεύτερον, καὶ τοῦ κατὰ τὴν δευτέραν τριταίου τὸν τρίτον. ἐνδέχεται δὲ τῶν ἄλλων ὡσαύτως ἐχόντων ἐν τῇ τρίτῃ τῶν ἡμερῶν ἦρχθαι δύο τριταίους ἄλλους, ἢ δύο τεταρταίους ἄλλους. ἐπεὶ γὰρ ἡ τετάρτη τῶν ἡμερῶν κατὰ τὴν τοιαύτην ὑπόθεσιν οὐδεμίαν ἔχει πρὸς τὴν τρίτην κοινωνίαν, ἐνδέχεται καὶ δύο τριταίους καὶ δύο τεταρταίους, καὶ τριταῖον καὶ τεταρταῖον ἕνα κατὰ τὴν τρίτην ἡμέραν ἄρξασθαι. θαυμάσαι δ’ ἔστι τὰς τοιαύτας ἐπιπλοκὰς συντιθέντων,3 εἰ μηδέποτε ἐνενόησαν ἐνδέχεσθαι τῶν δύο τύπων εἰς τὴν αὐτὴν ὥραν συνελθεῖν τοὺς παροξυσμοὺς, ὅπερ εἰ γένοιτο, διέφθαρται τὰ τῆς ἀνταποδόσεως αὐτοῖς γνωρίσματα. κατὰ γοῦν τὴν προκειμένην ὑπόθεσιν ἐγχωρεῖ τὸν μὲν ἐν τῇ πρώτῃ τῶν ἡμερῶν ἀρχόμενον τεταρταῖον ὥρᾳ δευτέρᾳ, τὸν δὲ τεταρταῖον ἑνδεκάτῃ.  τούτων δ’ οὕτως ἐχόντων, εἷς ἐν τῇ τετάρτῃ τῶν ἡμερῶν ἐστι παροξυσμός ὁ κατὰ τὴν δευτέραν ὥραν. οὐ μὴν ἕνα λέγουσί ποτε γενέσθαι κατὰ τὴν ὑποκειμένην ὑπόθεσιν, ἀλλ’ ἀεὶ δύο. θέασαι δ’ ὅπως ἐγχωρεῖ καὶ τρεῖς ἅμα παροξυσμοὺς εἰς μίαν ὥραν συνδραμεῖν, καὶ διὰ τοῦτ’ οὐκ ἀγνοηθῆναι τὴν ἐπιπλοκὴν τοῖς εἰδόσιν ἑκάστου τύπου τῶν ἁπλῶν διαγινώσκειν τὸ εἶδος. ὑποκείσθω γὰρ ἐν μὲν τῇ πρώτῃ τῶν ἡμερῶν ἦρχθαι τεταρταῖον ὥρᾳ τρίτῃ· ἐν δὲ τῇ δευτέρᾳ κατὰ τὴν αὐτὴν ὥραν τριταῖον· ἐν δὲ τῇ τρίτῃ κατὰ τὴν αὐτὴν ὥραν ἀμφημερινόν. ἀνάγκη δὴ τούτων ὑποκειμένων ἐν τῇ τετάρτῃ τῶν ἡμερῶν ὥρᾳ τρίτῃ γενέσθαι παροξυσμὸν ἕνα, τῶν τριῶν περιόδων ἐς ταὐτὸν ἀλλήλοις ἀφικομένων. ἀλλ’ οὐδεὶς αὐτῶν ἔγραψε τοῦτο, πάντες δὲ ὥσπερ ἐξ ἑνὸς στόματος ἐπὶ τῇ προειρημένῃ νῦν ὑποθέσει κατὰ τὴν τετάρτην ἡμέραν τρεῖς λέγουσι γενέσθαι παροξυσμούς. ἄν τέ τις (ἀναστρέψῃ) καθ’ ἑκάστην ἡμέραν ἅπαξ ὑποθῆται τὸν κάμνοντα παροξυνόμενον, ἔνιοι μὲν ἁπλῶς ἀμφημερινὸν ἀποφαίνονται, τινὲς δὲ ἐνδέχεσθαί φασι καὶ δύο τριταίους εἶναι καὶ τρεῖς τεταρταίους.

​Let us speak next of those who believe that there are only the three periods, not indeed diagnosing each from its own nature, but from the correspondences among the paroxysms. For this is how they themselves are accustomed to call the proportions of the paroxysms. Such people, even if they do not remain ignorant of the coming paroxysm forever like the former group, will necessarily be ignorant of it until the fourth or fifth day. For let it be assumed that on the first day one paroxysm occurred, on the second two, again on the third two, and on the fourth two. Now, it is possible for the complication of simple periods to be of such a kind that a quotidian began on the first day, a tertian on the second, and on the third day either a tertian or a quartan could begin (for this is unclear before the fifth day), and then on the fourth day there occurs the second paroxysm of the quartan that began on the first day and the second of the tertian that began on the second. And it is obvious that the fifth day will have two paroxysms: the second of the tertian that began on the third day, and the second of the quartan that began on the second day; and the sixth day will have the second of the quartan that began on the third, and the third of the tertian that began on the second. But, other things being the same, it is also possible that on the third day two other tertians or two other quartans began. For since the fourth day according to such a hypothesis has no connection with the third, it is possible for both two tertians and two quartans, or one tertian and one quartan, to begin on the third day. And one might wonder at those who construct such complications, if they never considered that it is possible for the paroxysms of two types to coincide at the same hour, which, if it should happen, destroys the signs of correspondence for them. At any rate, according to the proposed hypothesis, it is possible for the quartan beginning on the first day to occur at the second hour, and the other quartan at the eleventh hour. These things being so, there is only one paroxysm on the fourth day, the one at the second hour. Yet they never say that one occurs according to the assumed hypothesis, but always two. And see how it is possible for even three paroxysms to coincide at one hour, and how because of this the complication is not unknown to those who know how to diagnose the form of each of the simple types. For let it be assumed that on the first day a quartan began at the third hour; on the second, a tertian at the same hour; and on the third, a quotidian at the same hour. With these things assumed, it is necessary that on the fourth day at the third hour there occurs only one paroxysm, the three periods having arrived at the same point with one another. But none of them wrote this, and all, as if from one mouth, say that on the fourth day, under the hypothesis just mentioned, three paroxysms occur. And if, conversely, one assumes that the patient suffers a paroxysm once every day, some declare it simply a quotidian, while others say that it is possible to be both two tertians and three quartans.

Syntax notes3 items
  1. 3ἀνταποδόσεων

    While generally meaning 'repayment' or 'retribution,' here it is used as a medical technical term referring to the 'regular recurrence' or 'correspondence' of paroxysms. The subsequent phrase τὰς ἀναλογίας τῶν παροξυσμῶν (the proportions of the paroxysms) is presented as its equivalent.

  2. 3ἦρχθαι

    Perfect middle infinitive of ἄρχομαι (to begin). It is used in the accusative with infinitive construction inside the ὡς clause dependent on the impersonal verb ἐνδέχεται. The perfect tense denotes that the period of fever has already begun and is ongoing.

  3. 3συντιθέντων

    Present participle genitive plural, used substantively to mean 'those who construct (such complications).' It is governed as a genitive of cause/object by the verb of emotion θαυμάζω (here in the impersonal expression θαυμάσαι ἔστι, 'it is possible to wonder at').

Translated by Gemini 3.5 Flash (published 2026-05-22)urn:cts:greekLit:tlg0057.tlg049.humanitext-grc1:3#1